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CAS Number：1011529-10-4
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SMILES：Azvudine, CAS?1011529-10-4Azvudine, CAS?1011529-10-4,?Stock?370g,?Assay?99.7%,?White powder, Water?0.27%,?Single Impurity?0.3%.AzvudineAzvudine, also known as FNC and RO-0622, is a reverse transcriptase inhibitor potentially for the treatment of HIV infection. Azvudine showed synergism in combination with six approved anti-HIV drugs on both C8166 and PBMC. Azvudine also showed potent inhibition on NRTI-resistant strains (L74V and T69N). Treatment with Azudine and the protein biosynthesis inhibitor, cycloheximide (CHX), accelerated the inhibition of viral protein synthesis in the HTLV?1?infected cells.Product Details:Name: AzvudineCAS#: 1011529-10-4Chemical Formula: C9H11FN6O4Exact Mass: 286.0826Molecular Weight: 286.2234Elemental Analysis: C, 37.77; H, 3.87; F, 6.64; N, 29.36; O, 22.36Specification:Synonym: Azvudine; FNC; RO-0622; RO 0622; RO0622IUPAC/Chemical Name: 4-amino-1-((2R,3S,4R,5R)-5-azido-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-oneInChi Key: KTOLOIKYVCHRJW-XZMZPDFPSA-NInChi Code: InChI=1S/C9H11FN6O4/c10-5-6(18)9(3-17,14-15-12)20-7(5)16-2-1-4(11)13-8(16)19/h1-2,5-7,17-18H,3H2,(H2,11,13,19)/t5-,6-,7+,9+/m0/s1SMILES Code: O=C1N=C(N)C=CN1[C@H]2[C@@H](F)[C@@H]([C@](CO)(N=[N+]=[N-])O2)OAppearance: Solid powderPurity: >99% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility: Soluble in DMSOShelf Life: >2 years if stored properlyDrug Formulation: This drug may be formulated in DMSOStock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code: 2934.99.9001Certification: