Introduction
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CAS 1019331-10-2: S0859
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CAS Number: 1019331-10-2
Stock: 210g
Assay: 99.80%

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CAS Number:1019331-10-2
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SMILES:S0859, CAS 1019331-10-2S0859, CAS?1019331-10-2,?Stock?210g,?Assay?99.8%,?White powder, Water?0.5%,?Single Impurity?0.2%.S0859S0859 is a selective, high-affinity generic NBC inhibitor, potentially important for probing the transporter's functional role in heart and other tissues. S0859 reversibly inhibited NBC-mediated pH(i) recovery (K (i)=1.7 microM, full inhibition at approximately 30 microM). In HEPES-buffered superfusates, NHE-mediated pH(i) recovery was unaffected by 30 microM S0859. With CO(2)/HCO(3) (-) buffer, pH(i) recovery from intracellular alkalosis (mediated by Cl(-)/HCO(3) (-) and Cl(-)/OH(-) exchange) was also unaffected. .Product Details:Name: S0859CAS#: 1019331-10-2Chemical Formula: C29H24ClN3O3SExact Mass: 529.1227Molecular Weight: 530.039Elemental Analysis: C, 65.72; H, 4.56; Cl, 6.69; N, 7.93; O, 9.06; S, 6.05Specification:Synonym: S0859; S-0859; S 0859.IUPAC/Chemical Name: 2-chloro-N-((2'-(N-cyanosulfamoyl)-[1,1'-biphenyl]-4-yl)methyl)-N-(4-methylbenzyl)benzamideInChi Key: ITDBPOSLOROLMT-UHFFFAOYSA-NInChi Code: InChI=1S/C29H24ClN3O3S/c1-21-10-12-22(13-11-21)18-33(29(34)26-7-2-4-8-27(26)30)19-23-14-16-24(17-15-23)25-6-3-5-9-28(25)37(35,36)32-20-31/h2-17,32H,18-19H2,1H3SMILES Code: O=C(N(CC1=CC=C(C2=CC=CC=C2S(=O)(NC#N)=O)C=C1)CC3=CC=C(C)C=C3)C4=CC=CC=C4ClAppearance: Solid powderPurity: >99% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility: Soluble in DMSO, not in waterShelf Life: >2 years if stored properlyDrug Formulation: This drug may be formulated in DMSOStock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code: 2934.99.9001Certification: