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CAS Number：1024033-43-9
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SMILES：AZD4017, CAS 1024033-43-9AZD4017, CAS?1024033-43-9,?Stock?498g,?Assay?99.7%,?White powder, Water?0.29%,?Single Impurity?0.3%.AZD4017AZD4017 is a potent, selective, and orally bioavailable11??-HSD1 inhibitor (11??-hydroxysteroid dehydrogenase type 1 inhibitor). Inhibition of 11??-HSD1 is an attractive mechanism for the treatment of obesity and other elements of the metabolic syndrome. AZD4017 is a nicotinic amide derived carboxylic acid class of inhibitors that has good potency, selectivity, and pharmacokinetic characteristics. AZD4017) is an effective inhibitor of 11??-HSD1 in human adipocytes and exhibits good druglike properties and as a consequence was selected for clinical development.Product Details:Name: AZD4017CAS#: 1024033-43-9Chemical Formula: C22H33N3O3SExact Mass: 419.22426Molecular Weight: 419.58Elemental Analysis: C, 62.98; H, 7.93; N, 10.01; O, 11.44; S, 7.64Specification:Synonym:?AZD4017; AZD-4017; AZD 4017.IUPAC/Chemical Name:?2-[(3S)-1-[5-(cyclohexylcarbamoyl)-6-propylsulfanylpyridin-2-yl]-3-piperidyl]acetic acidInChi Key:?NCDZABJPWMBMIQ-INIZCTEOSA-NInChi Code:?InChI=1S/C22H33N3O3S/c1-2-13-29-22-18(21(28)23-17-8-4-3-5-9-17)10-11-19(24-22)25-12-6-7-16(15-25)14-20(26)27/h10-11,16-17H,2-9,12-15H2,1H3,(H,23,28)(H,26,27)/t16-/m0/s1SMILES Code:?O=C(O)C[C@H]1CN(C2=NC(SCCC)=C(C(NC3CCCCC3)=O)C=C2)CCC1Appearance:?Solid powderPurity:?>98% (or refer to the Certificate of Analysis)Shipping Condition:?Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition:?Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility:?Soluble in DMSO, not in waterShelf Life:?>2 years if stored properlyDrug Formulation:?This drug may be formulated in DMSOHS Tariff Code:?2934.99.9001Certification: