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CAS Number：1173900-33-8
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SMILES：AZD-6482(R), CAS 1173900-33-8AZD-6482(R), CAS?173900-33-8,?Stock?1639g,?Assay?98.58%,?White powder,?Water?0.17%,?Single Impurity?0.23%.AZD-6482(R)AZD6482 is a potent, selective and ATP competitive PI3K?? inhibitor (IC(50) 0.01 ??m). AZD6482 inhibited insulin-induced human adipocyte glucose uptake in vitro (IC(50) of 4.4 ??m). This is the first human target validation for PI3K?? inhibition as anti-platelet therapy showing a mild and generalized antiplatelet effect attenuating but not completely inhibiting multiple signaling pathways with an impressive separation towards primary hemostasis. AZD6482 at 'supratherapeutic' plasma concentrations may attenuate insulin signaling, most likely through PI3K?? inhibition.Product Details:Name: AZD6482CAS#: 1173900-33-8 (free base)Chemical Formula: C22H24N4O4Exact Mass: 408.17976Molecular Weight: 408.45Elemental Analysis: C, 64.69; H, 5.92; N, 13.72; O, 15.67Specification:Synonym: AZD6482; AZD-6482; AZD 6482.IUPAC/Chemical Name: (R)-2-((1-(7-methyl-2-morpholino-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl)ethyl)amino)benzoic acidInChi Key: IRTDIKMSKMREGO-OAHLLOKOSA-NInChi Code: InChI=1S/C22H24N4O4/c1-14-11-17(15(2)23-18-6-4-3-5-16(18)22(28)29)21-24-19(12-20(27)26(21)13-14)25-7-9-30-10-8-25/h3-6,11-13,15,23H,7-10H2,1-2H3,(H,28,29)/t15-/m1/s1SMILES Code: O=C(O)C1=CC=CC=C1N[C@@H](C2=CC(C)=CN(C2=NC(N3CCOCC3)=C4)C4=O)CAppearance: white powderPurity: >98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility: Soluble in DMSO, not in waterShelf Life: >2 years if stored properlyDrug Formulation: This drug may be formulated in DMSOStock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code: 2934.99.9001Certifications: