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CAS Number：1194506-26-7
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SMILES：Fruquintinib, CAS 1194506-26-7Fruquintinib, CAS?1194506-26-7,?Stock?293g,?Assay?99.7%,?White powder,?Water?0.24%,?Single Impurity?0.3%.FruquintinibFruquintinib, also known as HMPL-013, is an orally available, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFRs), with potential anti-angiogenic and antineoplastic activities. Upon oral administration, fruquintinib inhibits VEGF-induced phosphorylation of VEGFRs 1, 2, and 3 which may result in the inhibition of migration, proliferation and survival of endothelial cells, microvessel formation, the inhibition of tumor cell proliferation, and tumor cell death. Expression of VEGFRs may be upregulated in a variety of tumor cell types.Product Details:Name: FruquintinibCAS#: 1194506-26-7Chemical Formula: C21H19N3O5Exact Mass: 393.1325Molecular Weight: 393.39Elemental Analysis: C, 64.12; H, 4.87; N, 10.68; O, 20.34Specification:Synonym: Fruquintinib; HMPL013; HMPL 013; HMPL-013.IUPAC/Chemical Name: 6-((6,7-dimethoxyquinazolin-4-yl)oxy)-N,2-dimethylbenzofuran-3-carboxamideInChi Key: BALLNEJQLSTPIO-UHFFFAOYSA-NInChi Code: InChI=1S/C21H19N3O5/c1-11-19(20(25)22-2)13-6-5-12(7-16(13)28-11)29-21-14-8-17(26-3)18(27-4)9-15(14)23-10-24-21/h5-10H,1-4H3,(H,22,25)SMILES Code: O=C(C1=C(C)OC2=CC(OC3=C4C=C(OC)C(OC)=CC4=NC=N3)=CC=C12)NCAppearance: Solid powderPurity: >98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility: Soluble in DMSO, not in waterShelf Life: >2 years if stored properlyDrug Formulation: This drug may be formulated in DMSOStock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code: 2934.99.9001Certification: