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CAS Number：1260251-22-6
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SMILES：A Comprehensive Guide to CAS 1260251-22-6CAS 1260251-22-6 is a chemical compound that belongs to the class of pyridinylmethylthiazoles. This compound has received significant attention in recent years due to its potential medicinal properties. In this article, we will discuss the properties, uses, and synthesis of CAS 1260251-22-6.PropertiesCAS 1260251-22-6 has a molecular weight of 333.4 g/mol and a molecular formula of C17H14ClN3OS. It is a yellowish powder with a melting point of 200-205??C. The compound is sparingly soluble in water and soluble in organic solvents such as ethanol and DMSO.CAS 1260251-22-6 has been shown to exhibit potent anti-inflammatory and analgesic effects. It is believed to act by inhibiting the activity of an enzyme called 5-lipoxygenase, which is involved in the production of leukotrienes. Leukotrienes are known to play a role in the pathogenesis of inflammatory diseases such as asthma, rheumatoid arthritis, and inflammatory bowel disease.In addition to its anti-inflammatory properties, CAS 1260251-22-6 has also been shown to have antitumor activity. It is believed to act by inducing apoptosis (programmed cell death) in cancer cells. Studies have shown that the compound is effective against a range of cancer types, including breast, lung, and colon cancer.SynthesisCAS 1260251-22-6 can be synthesized using a multi-step process involving several chemical reactions. The synthesis starts with the reaction of 2-bromo-5-chloropyridine with 2-mercaptobenzothiazole in the presence of a base such as potassium carbonate. This reaction yields 2-(5-chloro-2-pyridyl)benzothiazole.The next step involves the reaction of 2-(5-chloro-2-pyridyl)benzothiazole with 2-(chloromethyl)pyridine in the presence of a base such as sodium hydride. This reaction yields 2-(5-chloro-2-pyridyl)-N-(pyridin-2-ylmethyl)benzothiazole.Finally, the compound is treated with trifluoroacetic acid to remove the protecting group and yield the final product, CAS 1260251-22-6.ConclusionCAS 1260251-22-6 is a promising compound with potential applications in the treatment of inflammatory diseases and cancer. Its anti-inflammatory and antitumor properties make it an attractive candidate for further research and development. The synthesis of this compound is complex but can be achieved using a multi-step process. Further studies are needed to fully understand the mechanism of action and potential therapeutic applications of CAS 1260251-22-6.