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CAS Number：1262132-81-9
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SMILES：Enarodustat(JTZ-951), CAS 1262132-81-9Enarodustat(JTZ-951), CAS 1262132-81-9,?Stock?894g,?Assay?98.74%,?White powder,?Water?0.24%,?Single Impurity?0.32%.Enarodustat?Enarodustat, also known as JTZ-951, is a prolyl hydroxylase inhibitor. JTZ-951 (enarodustat) stabilizes HIF-?? protein and induces erythropoiesis without effects on the function of vascular endothelial growth factor. Enarodustat increases endogenous erythropoietin levels in the treatment of anemia associated with chronic kidney disease (CKD). JTZ-951 induces erythropoiesis without affecting VEGF function. JTZ-951 may be a new oral candidate that increases and maintains hemoglobin concentrations in renal anemia patients.Product Details:Name: EnarodustatCAS#: 1262132-81-9 (free base)Chemical Formula: C17H16N4O4Exact Mass: 340.1172Molecular Weight: 340.34Elemental Analysis: C, 60.00; H, 4.74; N, 16.46; O, 18.80Specification:Related CAS #: 1262132-81-9 (free base)? ?1262131-60-1 (HCl)? ?1262133-55-0 (disodium)? ??Synonym: Enarodustat; JTZ-951; JTZ 951; JTZ951;IUPAC/Chemical Name: N-[7-hydroxy-5-(2-phenylethyl)[1,2,4]triazolo[1,5-a]pyridine-8-carbonyl]glycineInChi Key: NALAUGMPMIVAOW-UHFFFAOYSA-NInChi Code: InChI=1S/C17H16N4O4/c22-13-8-12(7-6-11-4-2-1-3-5-11)21-16(19-10-20-21)15(13)17(25)18-9-14(23)24/h1-5,8,10,22H,6-7,9H2,(H,18,25)(H,23,24)SMILES Code: O=C(O)CNC(C1=C(O)C=C(CCC2=CC=CC=C2)N3C1=NC=N3)=OAppearance: White powderPurity: >98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility: Soluble in DMSOShelf Life: >2 years if stored properlyDrug Formulation: This drug may be formulated in DMSOStock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code: 2934.99.9001Certification: