Products

CAS Number：1388651-30-6
Catalog Number:
Chemcial Name:
MW(Molecular Weight)：
MF(Molecular Formula):
SMILES：Elenbecestat(E2609), CAS 1388651-30-6Elenbecestat(E2609), CAS 1388651-30-6,?Stock 910g, Assay 98.62%, White powder, Water 0.22%, Single Impurity 0.31%.E2609Elenbecestat,also known as E2609 is a BACE1 inhibitor. By inhibiting BACE, a key enzyme in the production of A?? peptides, E2609 decreases the formation of these peptides which can aggregate into toxic oligomers and protofibrils and eventually form amyloid plaques in the brain. Elenbecestat has been shown to reduce A?? levels in cerebrospinal fluid, was investigated in two global phase 3 studies in early AD.Product Details:Name: Elenbecestat HClCAS#: Elenbecestat HClChemical Formula: C19H20Cl2F3N5O2SExact Mass: 437.1133Molecular Weight: 510.36Elemental Analysis: C, 44.72; H, 3.95; Cl, 13.89; F, 11.17; N, 13.72; O, 6.27; S, 6.28Specification:Related CAS #: 1388149-39-0 (free base)? ?Elenbecestat HCl? ??Synonym: Elenbecestat HCl; Elenbecestat hydrochloride, E2609; E-2609; E 2609, Elenbecestat.IUPAC/Chemical Name: N-[3-[(4aS,5R,7aS)-2-Amino-5-methyl-4,4a,5,7-tetrahydrofuro[3,4-d][1,3]thiazin-7a-yl]-4-fluorophenyl]-5-(difluoromethyl)pyrazine-2-carboxamide dihydrochlorideInChi Key: ATUMQXRZYKAHQJ-UTMNPRCUSA-NInChi Code: InChI=1S/C19H18F3N5O2S.2ClH/c1-9-12-7-30-18(23)27-19(12,8-29-9)11-4-10(2-3-13(11)20)26-17(28)15-6-24-14(5-25-15)16(21)22;;/h2-6,9,12,16H,7-8H2,1H3,(H2,23,27)(H,26,28);2*1H/t9-,12-,19-;;/m1../s1SMILES Code: O=C(C1=NC=C(C(F)F)N=C1)NC2=CC=C(F)C([C@@]34N=C(N)SC[C@]3([H])[C@@H](C)OC4)=C2.[H]Cl.[H]ClAppearance: White powderPurity: >98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility: Soluble in DMSOShelf Life: >3 years if stored properlyDrug Formulation: This drug may be formulated in DMSOStock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code: 2934.99.9001Certification: