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CAS Number：157716-52-4
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SMILES：Perifosine, CAS 157716-52-4:Perifosine,?CAS 157716-52-4,?Stock?125g,?Assay?98.43%,?White powder,?Water?0.19%,?Single Impurity?0.21%.PerifosinePerifosine is an orally active alkyl-phosphocholine compound with potential antineoplastic activity. Targeting cellular membranes, perifosine modulates membrane permeability, membrane lipid composition, phospholipid metabolism, and mitogenic signal transduction, resulting in cell differentiation and inhibition of cell growth. This agent also inhibits the anti-apoptotic mitogen-activated protein kinase (MAPK) pathway and modulates the balance between the MAPK and pro-apoptotic stress-activated protein kinase (SAPK/JNK) pathways, thereby inducing apoptosis. Perifosine has a lower gastrointestinal toxicity profile than the related agent miltefosine.Product Details:Name: PerifosineCAS#: 157716-52-4Chemical Formula: C25H52NO4PExact Mass: 461.3634Molecular Weight: 461.66Elemental Analysis: C, 65.04; H, 11.35; N, 3.03; O, 13.86; P, 6.71Specification:Synonym: KRX-0401; KRX 0401; KRX0401; NKA17; NSC639966; NSC 639966; NSC-639966; D 21266; D-21266; PerifosineIUPAC/Chemical Name: 1,1-dimethylpiperidin-1-ium-4-yl octadecyl phosphate.InChi Key: SZFPYBIJACMNJV-UHFFFAOYSA-NInChi Code: InChI=1S/C25H52NO4P/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-24-29-31(27,28)30-25-20-22-26(2,3)23-21-25/h25H,4-24H2,1-3H3SMILES Code: O=P(OC1CC[N+](C)(C)CC1)([O-])OCCCCCCCCCCCCCCCCCCAppearance: Solid powderPurity: >96% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility: Soluble in DMSO, not in waterShelf Life: >2 years if stored properlyDrug Formulation: This drug may be formulated in DMSOStock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code: 2934.99.9001Certification: