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CAS Number：1597402-27-1
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SMILES：JPH203, CAS 1597402-27-1JPH203, CAS 1597402-27-1,?Stock?906g,?Assay?98.63%,?White powder,?Water?0.34%,?Single Impurity?0.38%.KYT-0353JPH203, also known as KYT-0353, is a potent and selective LAT1 selective ( L-type amino acid transporter 1) inhibitor. JPH203 can very potently inhibit l-leucine uptake. JPH203 inhibits YD-38 cell growth. JPH203 up-regulated the population of apoptotic YD-38 cells through the activation of apoptotic factors, including caspases and PARP. (note: As per requested by patent owner, JPH203 can only be used solely for the purpose of obtaining information to be submitted to the regulatory authorization for obtaining a marketing approval of JPH203).Product Details:Name: JPH203 HClCAS#: 1597402-27-1 (2HCl)Chemical Formula: C23H21Cl4N3O4Exact Mass:Molecular Weight: 545.238Elemental Analysis: C, 50.67; H, 3.88; Cl, 26.01; N, 7.71; O, 11.74Specification:Related CAS #: 1597402-27-1 (2HCl)? ?1037592-40-7 (free base)? ?1597402-28-2 (complex with beta cyclodextrin)? ??Synonym: JPH203 dihydrochloride; JPH203 HCl; JPH203; JPH-203; JPH 203; KYT-0353; KYT 0353; KYT0353.IUPAC/Chemical Name: (S)-2-amino-3-(4-((5-amino-2-phenylbenzo[d]oxazol-7-yl)methoxy)-3,5-dichlorophenyl)propanoic acid dihydrochlorideInChi Key: MJSAOPNUSNNYQL-NTEVMMBTSA-NInChi Code: InChI=1S/C23H19Cl2N3O4.2ClH/c24-16-6-12(8-18(27)23(29)30)7-17(25)21(16)31-11-14-9-15(26)10-19-20(14)32-22(28-19)13-4-2-1-3-5-13;;/h1-7,9-10,18H,8,11,26-27H2,(H,29,30);2*1H/t18-;;/m0../s1SMILES Code: O=C(O)[C@@H](N)CC1=CC(Cl)=C(OCC2=C(OC(C3=CC=CC=C3)=N4)C4=CC(N)=C2)C(Cl)=C1.[H]Cl.[H]ClAppearance: white powderPurity: >98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility: Soluble in DMSOShelf Life: >2 years if stored properlyDrug Formulation: This drug may be formulated in DMSOStock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code: 2934.99.9001Certification: