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CAS Number：159858-22-7
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SMILES：Fmoc-Val-Cit-PAB-OH, CAS?159858-22-7:Fmoc-Val-Cit-PAB-OH,?CAS?159858-22-7,?Stock?206g,?Assay?99.13%,?White powder,?Water?0.26%,?Single Impurity?0.17%.Fmoc-Val-Cit-PAB-OHFmoc-Val-Cit-PAB-OH is a useful heterobifunational linker for making Antibody-Drug-Conjugates (ADC) for targeting drug delivery. The Val-Cit will specifically be cleaved by catepsin B. As this enzyme is only present in the lysosome, the ADC payload will only be released in the cell. The azido group will react with DBCO, BCN or other Alkyne group through click chemistry. The PEG spacer increases aqueous solubility.Product Details:Name: Fmoc-Val-Cit-PAB-OHCAS#: 159858-22-7Chemical Formula: C33H39N5O6Exact Mass: 601.29Molecular Weight: 601.704Elemental Analysis: C, 65.87; H, 6.53; N, 11.64; O, 15.95Specification:Synonym: Fmoc-Val-Cit-PAB-OH; ADC linker.IUPAC/Chemical Name: (9H-fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamateInChi Key: DALMAZHDNFCDRP-VMPREFPWSA-NInChi Code: InChI=1S/C33H39N5O6/c1-20(2)29(38-33(43)44-19-27-25-10-5-3-8-23(25)24-9-4-6-11-26(24)27)31(41)37-28(12-7-17-35-32(34)42)30(40)36-22-15-13-21(18-39)14-16-22/h3-6,8-11,13-16,20,27-29,39H,7,12,17-19H2,1-2H3,(H,36,40)(H,37,41)(H,38,43)(H3,34,35,42)/t28-,29-/m0/s1SMILES Code: O=C(N)NCCC[C@H](NC([C@H](C(C)C)NC(OCC1C(C=CC=C2)=C2C3=C1C=CC=C3)=O)=O)C(NC4=CC=C(CO)C=C4)=OAppearance: Solid powderPurity: >95% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility: Soluble in DMSOShelf Life: >2 years if stored properlyDrug Formulation: This drug may be formulated in DMSOStock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code: 2924297790Certification: