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CAS Number：1599432-08-2
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SMILES：NIBR-189, CAS?1599432-08-2:NIBR-189,?CAS?1599432-08-2,?Stock?256g,?Assay?99.14%,?White powder,?Water?0.19%,?Single Impurity?0.17%.NIBR-189NIBR-189 is a potent and selective EBI2 (GPR183) receptor antagonist (IC50 values are 11 and 15 nM for human and mouse EBI2 receptors respectively). NIBR-189 blocks migration of a monocyte cell line called U937, suggesting a functional role of the oxysterol/EBI2 pathway in these immune cells.Product Details:Name: NIBR-189CAS#: 1599432-08-2Chemical Formula: C21H21BrN2O3Exact Mass: 428.0736Molecular Weight: 429.314Elemental Analysis: C, 58.75; H, 4.93; Br, 18.61; N, 6.53; O, 11.18Specification:Synonym: NIBR-189; NIBR 189; NIBR189.IUPAC/Chemical Name: (E)-3-(4-bromophenyl)-1-(4-(4-methoxybenzoyl)piperazin-1-yl)prop-2-en-1-oneInChi Key: OFHXXBRBGWUOHR-NYYWCZLTSA-NInChi Code: InChI=1S/C21H21BrN2O3/c1-27-19-9-5-17(6-10-19)21(26)24-14-12-23(13-15-24)20(25)11-4-16-2-7-18(22)8-3-16/h2-11H,12-15H2,1H3/b11-4+SMILES Code: O=C(N1CCN(C(C2=CC=C(OC)C=C2)=O)CC1)/C=C/C3=CC=C(Br)C=C3Appearance: Solid powderPurity: >98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility: Soluble in DMSO, not in waterShelf Life: >2 years if stored properlyDrug Formulation: This drug may be formulated in DMSOStock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code: 2934.99.9001Certification: