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CAS Number：1632006-28-0
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SMILES：Esaxerenone, CAS 1632006-28-0Esaxerenone, CAS 1632006-28-0,?Stock?952g,?Assay?98.64%,?White powder,?Water?0.24%,?Single Impurity?0.32%.CS-3150, XL-550Esaxerenone, also known as CS-3150, XL-550, is a nonsteroidal antimineralocorticoid which was discovered by Exelixis and is now under development by Daiichi Sankyo Company for the treatment of hypertension, essential hypertension, hyperaldosteronism, and diabetic nephropathies. It acts as a highly selective silent antagonist of the mineralocorticoid receptor (MR), the receptor for aldosterone, with greater than 1,000-fold selectivity for this receptor over other steroid hormone receptors, and 4-fold and 76-fold higher affinity for the MR relative to the existing antimineralocorticoids spironolactone and eplerenone.Product Details:Name: EsaxerenoneCAS#: 1632006-28-0Chemical Formula: C22H21F3N2O4SExact Mass: 466.1174Molecular Weight: 466.4752Elemental Analysis: C, 56.65; H, 4.54; F, 12.22; N, 6.01; O, 13.72; S, 6.87Specification:Related CAS #: 1632006-28-0? ?880780-76-7? ?1072195-82-4 (+ isomer)? ?1072195-83-5 (- isomer)? ??Synonym: Esaxerenone; CS-3150; CS 3150; CS3150; XL-550; XL550; XL 550.IUPAC/Chemical Name: 1-(2-hydroxyethyl)-4-methyl-N-(4-(methylsulfonyl)phenyl)-5-(2-(trifluoromethyl)phenyl)-1H-pyrrole-3-carboxamideInChi Key: NOSNHVJANRODGR-UHFFFAOYSA-NInChi Code: InChI=1S/C22H21F3N2O4S/c1-14-18(21(29)26-15-7-9-16(10-8-15)32(2,30)31)13-27(11-12-28)20(14)17-5-3-4-6-19(17)22(23,24)25/h3-10,13,28H,11-12H2,1-2H3,(H,26,29)SMILES Code: CS(C1=CC=C(NC(C2=CN(CCO)C(C3=CC=CC=C3C(F)(F)F)=C2C)=O)C=C1)(=O)=OAppearance: White powderPurity: >98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility: Soluble in DMSO, not in waterShelf Life: >2 years if stored properlyDrug Formulation: This drug may be formulated in DMSOStock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code: 2934.99.9001Certification: