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CAS Number：1642303-38-5
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SMILES：ITI-214(phosphate), CAS 1642303-38-5ITI-214(phosphate), CAS 1642303-38-5,?Stock?841g,?Assay?98.83%,?White powder,?Water?0.14%,?Single Impurity?0.32%.ITI-214ITI-214 is an orally active, potent and Selective Inhibitors of Phosphodiesterase 1 for the Treatment of Cognitive Impairment Associated with Neurodegenerative and Neuropsychiatric Diseases. ITI-214 exhibited picomolar inhibitory potency for PDE1, demonstrated excellent selectivity against all other PDE families, and showed good efficacy in vivo. Currently, this investigational new drug is in Phase I clinical development and being considered for the treatment of several indications including cognitive deficits associated with schizophrenia and Alzheimer's disease, movement disorders, attention deficit and hyperactivity disorders, and other CNS and non-CNS disorders.Product Details:Name: ITI-214 phosphateCAS#: 1642303-38-5 (phosphate)Chemical Formula: C29H29FN7O5PExact Mass:Molecular Weight: 605.5672Elemental Analysis: C, 57.52; H, 4.83; F, 3.14; N, 16.19; O, 13.21; P, 5.11Specification:Related CAS #: 1642303-38-5 (phosphate)? ?1160521-50-5 (free base)? ??Synonym: ITI-214; ITI 214; ITI214; ITI-214 phosphate salt.IUPAC/Chemical Name: (6aR,9aS)-2-(4-(6-fluoropyridin-2-yl)benzyl)-5-methyl-3-(phenylamino)-5,6a,7,8,9,9a-hexahydrocyclopenta[4,5]imidazo[1,2-a]pyrazolo[4,3-e]pyrimidin-4(2H)-one phosphateInChi Key: ZPIAAFIYOPWWJL-RFPXDPOKSA-NInChi Code: InChI=1S/C29H26FN7O.H3O4P/c1-35-28(38)25-26(31-20-7-3-2-4-8-20)36(34-27(25)37-23-11-5-10-22(23)33-29(35)37)17-18-13-15-19(16-14-18)21-9-6-12-24(30)32-21;1-5(2,3)4/h2-4,6-9,12-16,22-23,31H,5,10-11,17H2,1H3;(H3,1,2,3,4)/t22-,23+;/m1./s1SMILES Code: O=C(C1=C(NC2=CC=CC=C2)N(CC3=CC=C(C4=NC(F)=CC=C4)C=C3)N=C1N56)N(C)C5=N[C@@]7([H])[C@]6([H])CCC7.O=P(O)(O)OAppearance: white powderPurity: >98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility: Soluble in DMSO, not in waterShelf Life: >2 years if stored properlyDrug Formulation: This drug may be formulated in DMSOStock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code: 2934.99.9001Certification: