Products

CAS Number：1792180-81-4
Catalog Number:
Chemcial Name:
MW(Molecular Weight)：
MF(Molecular Formula):
SMILES：Ritlecitinib, CAS 1792180-81-4Ritlecitinib, CAS 1792180-81-4,?Stock?900g,?Assay?99.39%,?White to off-white powder,?EOS is one of TOP GMP manufacturerRitlecitinibRitlecitinib, also known as PF-06651600, is a potent and selective JAK3 inhibitor. PF-06651600 is a potent and low clearance compound with demonstrated in vivo efficacy. The favorable efficacy and safety profile of this JAK3-specific inhibitor PF-06651600 led to its evaluation in several human clinical studies. JAK3 was among the first of the JAKs targeted for therapeutic intervention due to the strong validation provided by human SCID patients displaying JAK3 deficiencies.Product Details:Name: PF-06651600 free baseCAS#: 1792180-81-4 (free base)Chemical Formula: C15H19N5OExact Mass: 285.159Molecular Weight: 285.35Elemental Analysis: C, 63.14; H, 6.71; N, 24.54; O, 5.61Specification:Related CAS #:?1792180-81-4 (free base)? ?2140301-97-7 (malonate)? ?2192215-81-7 (tosylate)? ?2489392-29-0 (maleate)? ??Synonym:?Ritlecitinib; PF-06651600; PF 06651600; PF06651600; PF-6651600; PF 6651600; PF6651600;IUPAC/Chemical Name:?1-[(2S,5R)-2-Methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-2-propen-1-oneInChi Key:?CBRJPFGIXUFMTM-WDEREUQCSA-NInChi Code:?InChI=1S/C15H19N5O/c1-3-13(21)20-8-11(5-4-10(20)2)19-15-12-6-7-16-14(12)17-9-18-15/h3,6-7,9-11H,1,4-5,8H2,2H3,(H2,16,17,18,19)/t10-,11+/m0/s1SMILES Code:?C=CC(N1[C@@H](C)CC[C@@H](NC2=C3C(NC=C3)=NC=N2)C1)=OAppearance:?white powderPurity:?>98% (or refer to the Certificate of Analysis)Shipping Condition:?Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition:?Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility:?Soluble in DMSOShelf Life: >2 years if stored properlyDrug Formulation: This drug may be formulated in DMSOStock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code: 2934.99.9001Certification: