Products

CAS Number：1914078-41-3
Catalog Number:
Chemcial Name:
MW(Molecular Weight)：
MF(Molecular Formula):
SMILES：eCF506, CAS 1914078-41-3eCF506, CAS 1914078-41-3, Stock 900g, Assay 98.62%, White powder, Water 0.32%, Single Impurity 0.18%.eCF506eCF506 is the first, potent and selective SRC inhibitor that inhibits SRC at subnanomolar concentration (IC50 < 0.5 nM) with a 1000-fold selectivity over ABL. eCF506 exhibits excellent water solubility, an optimal DMPK profile and oral bioavailability, halts SRC-associated neuromast migration in zebrafish embryos without inducing life-threatening heart defects, and inhibits SRC phosphorylation in tumor xenografts in mice. eCF506 targets a molecule called Src tyrosine kinase that is required for breast cancer cells to grow and spread. eCF506 may be highly effective at blocking growth of breast cancer cells.Product Details:Name: eCF506CAS#: 1914078-41-3Chemical Formula: C26H38N8O3Exact Mass: 510.3067Molecular Weight: 510.643Elemental Analysis: C, 61.16; H, 7.50; N, 21.94; O, 9.40Specification:Synonym: eCF506; eCF-506; eCF 506.IUPAC/Chemical Name: tert-butyl (4-(4-amino-1-(2-(4-(dimethylamino)piperidin-1-yl)ethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-methoxyphenyl)carbamateInChi Key: GMPQGWXPDRNCBL-UHFFFAOYSA-NInChi Code: InChI=1S/C26H38N8O3/c1-26(2,3)37-25(35)30-19-8-7-17(15-20(19)36-6)22-21-23(27)28-16-29-24(21)34(31-22)14-13-33-11-9-18(10-12-33)32(4)5/h7-8,15-16,18H,9-14H2,1-6H3,(H,30,35)(H2,27,28,29)SMILES Code: COC1=CC(C2=NN(CCN3CCC(N(C)C)CC3)C4=NC=NC(N)=C42)=CC=C1NC(OC(C)(C)C)=OAppearance: Solid powderPurity: >98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility: Soluble in DMSO, not in waterShelf Life: >2 years if stored properlyDrug Formulation: This drug may be formulated in DMSOStock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code: 2934.99.9001Certification: