Products

CAS Number：1953133-47-5
Catalog Number:
Chemcial Name:
MW(Molecular Weight)：
MF(Molecular Formula):
SMILES：Giredestrant (GDC-9545): CAS 1953133-47-5Giredestrant (GDC-9545): CAS 1953133-47-5,?Stock?322g,?Assay?99.29%,?White to off-white powder,?EOS is one of TOP GMP manufacturerGiredestrant (GDC-9545)Giredestrant, also known as GDC-9545 and RG6171, is a SERD. GDC-9545 is an orally available selective estrogen receptor degrader/downregulator (SERD), with potential antineoplastic activity. Upon oral administration, SERD GDC-9545 specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that promotes ER degradation.Product Details:Name: GiredestrantCAS#: 1953133-47-5 (free base)Chemical Formula: C27H31F5N4OExact Mass: 522.2418Molecular Weight: 522.564Elemental Analysis: C, 62.06; H, 5.98; F, 18.18; N, 10.72; O, 3.06Specification:Synonym:?GDC-9545; GDC9545; GDC 9545; RG6171; RG-6171; RG 6171; Giredestrant;IUPAC/Chemical Name:?3-((1R,3R)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2,2-difluoropropan-1-olInChi Key:?GQCXHIKRWBIQMD-AKJBCIBTSA-NInChi Code:?InChI=1S/C27H31F5N4O/c1-16-9-20-19-5-2-3-6-23(19)34-25(20)26(36(16)14-27(31,32)15-37)24-21(29)10-17(11-22(24)30)33-18-12-35(13-18)8-4-7-28/h2-3,5-6,10-11,16,18,26,33-34,37H,4,7-9,12-15H2,1H3/t16-,26-/m1/s1SMILES Code:?C[C@@H]1CC(C2=C(N3)C=CC=C2)=C3[C@@H](C4=C(C=C(C=C4F)NC5CN(C5)CCCF)F)N1CC(CO)(F)FAppearance:?powderPurity:?>98% (or refer to the Certificate of Analysis)Shipping Condition:?Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition:?Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility:?Soluble in DMSOShelf Life:?>2 years if stored properlyDrug Formulation:?This drug may be formulated in DMSOHS Tariff Code:?2934.99.9001Certification: