Products

CAS Number：2114339-57-8
Catalog Number:
Chemcial Name:
MW(Molecular Weight)：
MF(Molecular Formula):
SMILES：Amcenestrant, CAS 2114339-57-8Amcenestrant, CAS 2114339-57-8,?Stock?139g,?Assay?99.76%,?White powder,?EOS is one of TOP GMP manufacturerAmcenestrantAmcenestrant, also known as SAR439859, is an orally available, nonsteroidal selective estrogen receptor degrader/downregulator (SERD), with potential antineoplastic activity. Upon oral administration, SERD SAR439859 specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that promotes ER degradation. This prevents ER-mediated signaling and inhibits both the growth and survival of ER-expressing cancer cellsProduct Details:Name:?AmcenestrantCAS#: 2114339-57-8Chemical Formula: C31H30Cl2FNO3Exact Mass: 553.1587Molecular Weight: 554.4834Elemental Analysis: C, 67.15; H, 5.45; Cl, 12.79; F, 3.43; N, 2.53; O, 8.66Specification:Synonym:?Amcenestrant, SAR439859; SAR-439859; SAR 439859;IUPAC/Chemical Name:?6-(2,4-Dichlorophenyl)-5-[4-[(3S)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7H-benzo[7]annulene-2-carboxylic acidInChi Key:?KISZAGQTIXIVAR-VWLOTQADSA-NInChi Code:?InChI=1S/C31H30Cl2FNO3/c32-23-8-12-27(29(33)18-23)28-4-1-3-21-17-22(31(36)37)7-11-26(21)30(28)20-5-9-24(10-6-20)38-25-13-16-35(19-25)15-2-14-34/h5-12,17-18,25H,1-4,13-16,19H2,(H,36,37)/t25-/m0/s1SMILES Code:? ?O=C(C1=CC=C2C(CCCC(C3=CC=C(Cl)C=C3Cl)=C2C4=CC=C(O[C@@H]5CN(CCCF)CC5)C=C4)=C1)OAppearance:?Solid powderPurity:?>98% (or refer to the Certificate of Analysis)Shipping Condition:?Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition:?Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility:?Soluble in DMSOShelf Life:?>3 years if stored properlyDrug Formulation:?This drug may be formulated in DMSOCertification: