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CAS Number：218600-53-4
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SMILES：Bardoxolone methyl, CAS: 218600-53-4Bardoxolone methyl, CAS: 218600-53-4, Stock?162g,?Assay?99.66%,?White powder,?EOS is one of TOP GMP manufacturerBardoxolone methylBardoxolone methyl (also known as ??RTA 402?? and ??CDDO-methyl ester??) is an orally-available first-in-class synthetic triterpenoid belonging to the antioxidant inflammation modulator (AIM) class. It is the most potent known inducer of the Nrf2 pathway to enter clinical development and works to suppress both oxidative stress and inflammation. Bardoxolone methyl is currently being developed by Reata Pharmaceuticals, Inc. in partnership with Abbott Laboratories and Kyowa Hakko Kirin, for the treatment of advanced chronic kidney disease (CKD) in type 2 diabetes mellitus patients.Product Details:Name: Bardoxolone methylCAS#: 218600-53-4Chemical Formula: C32H43NO4Exact Mass: 505.31921Molecular Weight: 505.69Elemental Analysis: C, 76.00; H, 8.57; N, 2.77; O, 12.66Specification:Synonym:?Bardoxolone methyl; CDDO Methyl ester; CDDOMe; NSC 713200; RTA 402; RTA-402; RTA402; TP-155; TP155; TP 155IUPAC/Chemical Name:?(4aS,6aR,6bS,12aS,14aR,14bR)-methyl 11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicene-4a-carboxylateInChi Key:?WPTTVJLTNAWYAO-OROHISIGSA-NInChi Code:?InChI=1S/C32H43NO4/c1-27(2)11-13-32(26(36)37-8)14-12-31(7)24(20(32)17-27)21(34)15-23-29(5)16-19(18-33)25(35)28(3,4)22(29)9-10-30(23,31)6/h15-16,20,22,24H,9-14,17H2,1-8H3/t20-,22?,24+,29+,30-,31-,32+/m1/s1SMILES Code:?O=C([C@]1(CC[C@@]2(C)[C@]3(C)CCC4C(C)(C)C(C(C#N)=C[C@]4(C)C3=C5)=O)CCC(C)(C)C[C@]1([H])[C@@]2([H])C5=O)OCAppearance:?White to off-white solid powderPurity:?>98% (or refer to the Certificate of Analysis)Shipping Condition:?Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition:?Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility:?Soluble in DMSO, not in waterShelf Life:?>2 years if stored properlyDrug Formulation:?This drug may be formulated in DMSOHS Tariff Code:?2934.99.9001Certification: