Introduction
-
Imisopasem manganese(M40403), CAS 218791-21-0
(World's Largest Pharmaceutical Supplier)
CAS Number: 218791-21-0
Stock: 890g
Assay: 98.64%

Details
CAS Number:218791-21-0
Catalog Number:
Chemcial Name:
MW(Molecular Weight):
MF(Molecular Formula):
SMILES:Imisopasem manganese(M40403), CAS 218791-21-0Imisopasem manganese(M40403), CAS 218791-21-0,?Stock?890g,?Assay?98.64%,?White powder,?Water?0.24%,?Single Impurity?0.32%.M40403Imisopasem manganese , also known as M40403, or GC4419, is a manganese-based non-peptidyl mimetic of the human mitochondrial manganese superoxide dismutase (MnSOD), with potential antioxidant and chemo/radioprotective activities. Upon administration, imisopasem manganese mimics the activity of MnSOD and scavenges reactive oxygen species (ROS), such as superoxide anion, which prevents oxygen free radical damage to macromolecules such as DNA. This reduces ROS-mediated lipid peroxidation, prevents apoptosis and protects against oxygen free radical-induced toxicity in normal tissues.Product Details:Name: Imisopasem manganeseCAS#: 218791-21-0Chemical Formula: C21H35Cl2MnN5Exact Mass:Molecular Weight: 483.38Elemental Analysis: C, 52.18; H, 7.30; Cl, 14.67; Mn, 11.37; N, 14.49Specification:Synonym: M40403; M 40403; M-40403; CG4419; CG 4419; CG-4419; SC72325; SC-72325; SC 72325; Imisopasem manganeseIUPAC/Chemical Name: Manganese, dichloro[(4aR,13aR,17aR,21aR)-1,2,3,4,4a,5,6,12,13,13a,14,15,16,17,17a,18,19,20,21,21a-eicosahydro-11,7-nitrilo-7Hdibenzo[b,h][1,4,7,10]tetraazacycloheptadecine-??N5,??N13,??N18,??N21,??N22]-, (PB-7-11-2344'3')-.InChi Key: WXEMWBBXVXHEPU-QUDNGXPYSA-LInChi Code: InChI=1S/C21H35N5.2ClH.Mn/c1-3-10-20-18(8-1)22-12-13-23-19-9-2-4-11-21(19)25-15-17-7-5-6-16(26-17)14-24-20;;;/h5-7,18-25H,1-4,8-15H2;2*1H;/q;;;+2/p-2/t18-,19-,20-,21+;;;/m1.../s1SMILES Code: [H][N@]1([C@H]2[C@H]3CCCC2)CC4=[N]5C(C[N]6([H])[C@H]7CCCC[C@H]7[N@@]([Mn]861(Cl)5Cl)([H])CC[N@@]38[H])=CC=C4Appearance: white powderPurity: >98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility: Soluble in DMSO, not in waterShelf Life: >2 years if stored properlyDrug Formulation: This drug may be formulated in DMSOStock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code: 2934.99.9001Certification: