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CAS Number：314245-33-5
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SMILES：IU1, CAS 314245-33-5IU1, CAS 314245-33-5,?Stock?920g,?Assay?98.74%,?White powder,?Water?0.21%,?Single Impurity?0.3%.IU1IU1 is a selective USP14 inhibitor. IU1 prevents ventilator-induced lung injury in rats. IU1 inhibits the catalytic activity of proteasome-associated Usp14 in vitro (IC50 < 4 ??M). IU1 stimulates proteasome activity and substrate degradation. USP14 removes the ubiquitin chain of I-??B, therefore inducing I-??B degradation and increasing cytokine release.Product Details:Name: IU1CAS#: 314245-33-5Chemical Formula: 18H21FN2OExact Mass: 300.16379Molecular Weight: 300.37Elemental Analysis: C, 71.98; H, 7.05; F, 6.32; N, 9.33; O, 5.33Specification:Synonym: IU1; IU-1; IU 1IUPAC/Chemical Name: 1-(1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-(pyrrolidin-1-yl)ethan-1-oneInChi Key: JUWDSDKJBMFLHE-UHFFFAOYSA-NInChi Code: InChI=1S/C18H21FN2O/c1-13-11-17(18(22)12-20-9-3-4-10-20)14(2)21(13)16-7-5-15(19)6-8-16/h5-8,11H,3-4,9-10,12H2,1-2H3SMILES Code: CC1=CC(C(CN2CCCC2)=O)=C(C)N1C3=CC=C(F)C=C3Appearance: white powderPurity: >98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Solubility: Soluble in DMSO, not in waterShelf Life: >2 years if stored properlyDrug Formulation: This drug may be formulated in DMSOStock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).HS Tariff Code: 2934.99.9001Certification: