Efficacy and Safety of Selinexor

Nov 26, 2018
1.Selinexor and intermediates
Selinexor 1393477-72-9  intermediate: 27126-93-8
Selinexor 1393477-72-9  intermediate: 317319-15-6
Selinexor 1393477-72-9  intermediate: 1333154-10-1
Selinexor 1393477-72-9  intermediate: 1388842-43-0
Selinexor 1393477-72-9  intermediate: 1421923-95-6
Selinexor 1393477-72-9  intermediate: 1421923-96-7
Selinexor 1393477-72-9  intermediate: 54608-52-5

2.ROS-Selinexor



3.
Name: Selinexor free base
CAS#: 1393477-72-9
Chemical Formula: C17H11F6N7O
Exact Mass: 443.09293
Molecular Weight: 443.31
Elemental Analysis: C, 46.06; H, 2.50; F, 25.71; N, 22.12; O, 3.61

Synonym: KPT-330; KPT330; KPT 330; Selinexor.

IUPAC/Chemical Name: (Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyrazin-2-yl)acrylohydrazide

InChi Key: DEVSOMFAQLZNKR-RJRFIUFISA-N

InChi Code: InChI=1S/C17H11F6N7O/c18-16(19,20)11-5-10(6-12(7-11)17(21,22)23)15-26-9-30(29-15)4-1-14(31)28-27-13-8-24-2-3-25-13/h1-9H,(H,25,27)(H,28,31)/b4-1-

SMILES Code: O=C(NNC1=NC=CN=C1)/C=C\N2N=C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)N=C2

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